If you are new to administering subcutaneous fluids for dogs (i.e. SQ fluids), you may be feeling a bit overwhelmed by the process. But help is here. Integrative veterinarian Dr. Julie Buzby provides detailed step-by-step instructions (complete with pictures and video). Also, she answers some common FAQs to empower you to confidently give your dog subcutaneous fluids.

Finding out you need to give your beloved senior dog subcutaneous fluids can come with a mix of emotions. On one hand, it is something concrete you can do to help your dog. But on the other hand, it involves sticking a needle in your dog and using a complicated-looking fluid setup.
I understand that the idea of giving your dog subcutaneous fluids can be a bit intimidating. But it doesn’t have to be. This article provides a step-by-step administration guide and answers some FAQs to take the fear and mystery out of giving your dog subcutaneous fluids. I know you can do it!
If you are looking for the answer to a specific question regarding fluids, you may want to skip to the FAQs section (or if you don’t see the answer there, call your vet). Otherwise, let’s start looking at the nuts and bolts of the process.
What equipment do I need to administer subcutaneous fluids?
The first step to learning how to give fluids to your dog is ensuring you are prepared and have all the materials ready. Your vet will give you most of the supplies you need, but there are some things you can gather from your home that might make the process easier.
To set up the fluids, you need:
- Coat hanger or some other way to hang the fluid bag
- Bag of fluids
- Drip set (also called a fluid line or extension line)
- Needle (usually an 18 gauge)
- Sharpie
- Paper towels
- High value rewards for your dog
- Someone to help you restrain your dog (if necessary)
- A blanket or towel if your dog likes being wrapped up
- And of course, your dog

How do I assemble the subcutaneous fluids set?
Now that you have your materials gathered, you are ready to follow the steps to set up the fluids.
(Note: These instructions start you from “square one” of assembling the fluid administration set. However, it is possible that the veterinary team may have already done some of these steps for you. Also, it is worth noting that your vet might have demonstrated the technique in a slightly different order. There are multiple ways to arrive at the same endpoint.)
Attaching the fluid line to the bag
1. Remove the fluid bag and fluid line from their packaging.
2. Examine the fluid line. There is usually a white “lock” (i.e. clamp or fluid rate controller) with a rolling mechanism on the line. Typically, this flow controller is set in the “open” position. You can tell that it is “open” because the clamp will slide up and down the line. Close the clamp by moving the roller all the way down. This will squeeze the tubing to close the line, and the clamp should no longer move.

3. Next, pick up the fluid bag. On one end there is a rubbery tab (usually it is white) or a plastic cap. Remove this cap or tab from the fluid bag and set it aside (or throw it in the trash as you won’t need it again). You may need to pull fairly hard on the tab to get it off. Be careful not to let the newly exposed opening on the fluid bag touch anything because this part should remain clean.
NOTE: You can do this while the bag is hanging or lying on the table as no fluid will leak out until the bag is punctured by the fluid line.
4. Go back to the fluid line and look for the end with a pointy, plastic tip that has a cover on it. Remove the cover from the tip. Be careful not to touch the pointed part as it needs to remain clean.

5. Insert the white pointed end of the fluid line into the fluid bag where you opened it in step 3. You may have to use a forceful twisting motion to push the point all the way into the bag. It is important that the point is secured properly to prevent leaks from occurring.

NOTE: Now the bag is punctured and has a hole in it. You do not want to remove the fluid line from the bag, otherwise the fluids will spill.
Hanging the bag up and marking the fluid amount
6. Now that the fluid line is attached to the fluid bag, you can hang the bag up (if you haven’t already). This is where a coat hanger can come in handy. Alternatively, you can hand the bag to your assistant.
TIP: If you hang the bag higher, gravity will assist you and make the fluids flow faster (therefore making the administration faster). But, you want to still be able to see the bag to monitor the amount of fluids given. Ideally, the bag would be about three feet above your dog’s back.
7. Look at the lines measuring the fluids on the bag and determine how many milliliters (mls) of fluid each line represents (usually 100 ml, but could be 50 ml for a smaller bag). Then use a Sharpie pen to make a line indicating the “stop point” that corresponds to the volume of subcutaneous fluids you need to give your dog. This dosage will vary with each dog and will be based on your veterinarian’s recommendations.

NOTE: It is much easier to measure the amount of fluids before you start administering them. Try to remember to take the time to do this first.
Preparing the fluid line
8. Look for a clear chamber on the fluid line at the end closest to the bag and squeeze the bulb to allow fluids to fill the chamber about halfway.
NOTE: Depending on how you have the bag positioned, squeezing the bulb can add or remove fluid from the chamber. If the bag is upright (i.e. with the chamber below the bag), squeezing the bulb will cause more fluid to enter the chamber. But if you turn the bag upside down so the chamber is on top and then squeeze the bulb, it will push some fluid back into the bag. This is helpful to remember if you accidentally fill too much of the chamber with fluids.
9. Now look at the end of the fluid line not inserted into the fluid bag. There is a plastic cap covering this end. Carefully remove the cap. Be sure not to touch the end of the line, as this should remain as clean as possible too. Also, keep the cap clean and nearby because you may need it later.
10. Open the fluid flow control clamp on the fluid line by rolling the circle upward. Allow fluid to flow through the line until the entire line is filled and a small amount of fluid drips out of the uncapped end. Then close the clamp to stop the flow of fluid.

NOTE: This step helps ensure you don’t accidentally inject air under your dog’s skin when you first start running the fluids. A few bubbles of air under the skin aren’t a big deal, but a fluid line full of air can be uncomfortable for your dog until the body absorbs it. Thankfully, it isn’t usually dangerous, though.
11. Either temporarily replace the cap on the fluid line or hold onto the fluid line close to the end to keep the tip from touching anything. Then pick up your needle and remove the clear cap at the base or peel away the paper and plastic wrapping to expose the hub of the needle. This end should be kept clean too.
12. Attach the exposed base (i.e. hub) of the needle to the exposed end of the fluid line. Be sure it is firmly attached to prevent leaks or the needle falling off. Some fluid lines also have a locking collar that you twist around the base of the needle once you attach it, but others do not. Both types work fine.
How do I give subcutaneous fluids to my dog?
Now that the fluids are fully assembled, you are ready to give them to your dog.
Preparing yourself and your dog
1. Choose a location that is comfortable for you and your dog. If your dog is small, I recommend having him or her on a table or in your lap. Some of my clients will even wrap their small dog in a towel to help him or her feel secure and safe. On the other hand, large dogs usually do best standing on the floor or lying down—either in a dog bed or nestled between your outstretched legs.

NOTE: The fluid bag should be hanging about three feet above your dog as mentioned above. Make sure the needle on the fluid line can easily reach your dog without any tension in the line.
2. Properly restrain your dog so he or she is not moving around a lot. A high-value treat can provide extra encouragement for your dog to stay still. One of my favorite tricks is to wipe peanut butter on the wall at the level of the dog’s nose. Then, the dog will stay in one place and be busy licking the peanut butter instead of paying attention to you and the fluid therapy.
If you need help keeping your dog still, ask a friend or family member to assist you. They can give your dog a gentle hug by wrapping one arm under the dog’s neck and placing the other arm over the dog’s back or around the dog’s back end.
TIP: Finding ways to keep your dog still is quite helpful. The more your dog moves, the slower the fluids will run. Also, if your dog is still, he or she is less likely to notice the fluids being administered.
Inserting the needle.
3. Locate the loose skin that is between your dog’s shoulder blades. This is where you will insert the needle. (It is also possible to give SQ fluids over your dog’s hip, but this location tends to be used less commonly.)

4. Carefully uncap the needle. (Save this cap for later).
5. While holding the needle in one hand, use the other hand to gently pinch and slightly lift the loose skin between the shoulders to create a “tent.” I like to squeeze, rub, and wiggle the skin a bit as I hold it up. This is a good way to distract your dog from the needle poke.
6. Hold the needle at the base of this tent and begin inserting the tip of the needle into the skin at a 30 to 45 degree angle. Fully submerge the length of the needle under your dog’s skin. Then release the tent but continue to hold the needle in place.
TIP: Inserting the needle should be a firm and steady motion. You do not want to jab it in or go slowly and shakily. If you want to practice inserting a needle before administering fluids to your dog, try performing the same motion on an orange or banana. This will give you a feel for how much pressure to use. (Be sure to discard these practice needles because they will be too dull to use on your dog.)
Administering the fluids
7. Use one hand to continue to hold the needle in place. Use the other hand to release the rolling lock of the clamp on the fluid line. You should begin to see the fluids dripping into the chamber and flowing through the fluid line. The clamp should be “wide open” so that the fluids are running quickly.
TIP: If fluids are dripping down the side of your dog instead of going under the skin, you may have accidentally pushed the needle out through the other side of your dog’s skin. Simply withdraw the needle slightly so that the tip is under the skin again and continue giving the fluids. If that doesn’t work, temporarily shut off the fluids, withdraw the needle, and insert it into a slightly different location.
8. As the fluid therapy continues, keep your dog still and calm. Use a gentle voice to reward him or her for standing still.
TIP: If the fluids are running slowing, try to gently reposition the needle under the skin or change the angle without removing the needle. Also, ensure the clamp on the fluid line is open all the way.

9. Keep an eye on the Sharpie line you made earlier to monitor the fluid volume you have given so far, and keep a hand on the needle at all times.
NOTE: Sometimes you will give the full volume of fluids in one location. Other times your vet may instruct you to divide the fluid volume up over multiple areas. If this is the case, follow the instructions for shutting off the fluids and withdrawing the needle (steps 10 and 11) and then repeat the fluid administration process starting with step 5.
Removing the needle
10. When the fluids reach the line you’d made with the Sharpie pen, then your dog has received the full dose. Next, roll the lock of the clamp on the fluid line back into the closed position. Once the fluids have stopped flowing, use one hand to completely back the needle out of your dog’s skin.
11. Once you have removed the needle completely, use your fingers, gauze, or a paper towel to put pressure on the spot where the needle was. This will help prevent bleeding or fluids leaking out.
12. Carefully place the cap back on the needle. Pay close attention to what you are doing because recapping the needle is when most people accidentally poke themselves.
13. Reward your dog for being so good during the procedure. And pat yourself on the back because you have finished the hard part. All you have left is to put things away.
Putting the fluid set away
14. Remove the needle (with its cap on) from the end of the fluid line. Replace it with a new clean needle as described above. This will help prevent bacteria from growing in the fluid set and ensure you always have a clean, fresh needle for the next time.

15. Double check that nothing is leaking and that you have properly capped the needle. Store the bag at room temperature in a safe place until it is time for the next dose. Since the fluid set is already assembled, you can make your new Sharpie mark for the next time. Then you’ll be ready to start on step 1 of the “how do I give subcutaneous fluids” when the next fluid needs administered.
Phew! You did it! Hopefully, administering subcutaneous fluids wasn’t as difficult or scary as you thought. But even if you did struggle with it the first time, remember that it should get easier as you do it more often. You can always consult with the veterinary team if you need some additional help.
Also, you may want to watch the video below.
How to give SQ fluids: A step-by-step video tutorial
To help you feel more confident and add to your knowledge base, I’ve created this step-by-step video tutorial of how to give subcutaneous fluids to your dog at home. Check it out, and then read on for answers to eight FAQs.
Fluid FAQS
After you finish giving your dog the fluids (or before you start), you might also have some questions that pertain to aspects other than just how to administer the fluids. Hopefully, you will find the answers in my fluid FAQs section helpful. If not, or if you have other concerns, please reach out to your vet.
FAQ #1: Why might my dog need subcutaneous fluids?
Vets use fluid therapy to treat a variety of conditions. In the hospital setting, the vet can administer either subcutaneous fluids or IV (intravenous) fluids. SQ fluids are great for dogs who are mildly dehydrated and need a quick and easy fluid boost before heading home with their parents. On the other hand, the vet will use IV fluids for dogs who are sicker, undergoing anesthesia, or hospitalized.
In the home setting, IV fluids would be difficult to administer and potentially dangerous. However, subcutaneous fluids are safe and simple to do at home.
The most common use for at-home subcutaneous fluid administration is to help improve quality of life and slow disease progression in cases of chronic kidney disease in dogs. However, the vet may also recommend it for other conditions that cause dehydration.

FAQ #2: Are there alternatives to subcutaneous fluids?
Other than in-hospital IV fluids (as mentioned in FAQ #1) and subcutaneous fluids, the other way to get more fluids into a dog is oral fluid therapy. This may involve:
- Ensuring the water dish is always full of fresh, clean water to promote drinking
- Adding water to dry food
- Feeding canned food since it is about 75-80% water
Sometimes these measures can be sufficient in the early stages of kidney disease in dogs or for other minor issues. However, there often comes a time when the dog needs more fluids than oral fluids alone can provide. This is where subcutaneous fluids can come to the rescue.
However, this doesn’t mean you have to do the subcutaneous fluids at home. Another option is to bring your dog to the veterinary clinic and have one of the veterinary team members administer the fluids if you would be more comfortable with that approach.
FAQ #3: What are the side effects of subcutaneous fluids in dogs?
Thankfully, fluids are very safe, and the side effects are minor.
Migration of the fluids
The most common thing that dog parents notice right away is that their dog might look like he or she has a camel hump. This is completely normal! The hump is where the fluids are sitting because they haven’t been absorbed yet.
You may notice this hump stays between the shoulder blades, falls to the side so your dog looks lopsided, or sometimes even divides between two or three places or slides down to the chest or legs. Over the next four to six hours, the fluids will diffuse and be absorbed, and the hump will resolve.
If the subcutaneous fluids are not fully absorbed by the time you are supposed to give the next dose, please contact your veterinarian before administering any further fluids. Based on the information you provide (or an examination if warranted), your vet can advise you on how to proceed.
Bleeding or leaking at the administration site
The other side effect dog parents may notice is bleeding or leaking at the site where the needle was inserted. This happens sometimes and is not usually a concern. If the skin becomes tight from all the fluids, some of the fluid may squeeze back out. Or sometimes the needle may accidentally hit a small skin blood vessel and cause your dog’s skin to bleed (just like if we got poked or bit by a bug).
If this happens, apply pressure to the area for about 30 seconds and the leaking or bleeding should resolve. If it doesn’t, or you have questions or concerns, please contact your veterinarian.
Minor pain or soreness
Additionally, some dog parents notice that their dogs seem to be painful or irritated at the spot where the needle was inserted. Just like when you get a vaccine, sometimes the area can be a little sore.
If you think the fluid “hump” is uncomfortable for your dog, you can try massaging the area gently to release some of the tension. Or, if the injection site seems to be bothering him or her, you can also apply a cold pack wrapped in a towel for two to three minutes.

However, if you think your dog is unusually painful after subcutaneous fluids, please don’t hesitate to reach out to your vet for reassurance and guidance as well.
FAQ #4: How much subcutaneous fluid should I give my dog?
Your dog’s veterinarian will help you figure out the volume and frequency of subcutaneous fluids that is best for your dog. This will depend on your dog’s size and the reason for the fluids, among other things. The fluid volume or frequency may also change as your dog’s kidney failure, or other condition, progresses.
FAQ #5: Is it normal for my dog to pee a lot after subcutaneous fluids?
Yes, some dogs will urinate more after fluid administration because they are no longer dehydrated. If this happens, it is a good sign because it means that the fluids have been absorbed and are working. But if you become concerned that your dog is peeing too much, please contact your veterinarian.
FAQ #6: Will my dog still drink water after subcutaneous fluids?
Since you gave your dog some fluids under the skin, he or she may or may not feel the need to drink as much water for a bit. However, clean, fresh water should always be readily available for your dog in case he or she wants it.
FAQ #7: Will my dog be tired after receiving subcutaneous fluids?
Your canine companion might be tired or even a rather lethargic dog after receiving fluids (especially if he or she is easily stressed). It is okay if your dog wants to rest for a few hours after therapy. If the lethargy continues or you notice other symptoms, please contact your veterinarian.

FAQ #8: Can I warm up the fluids before giving them to my dog?
While you should always store fluids at room temperature, sometimes warming them up can make administration less uncomfortable for your dog. To warm up the fluids, fill a sink or large bowl with warm water. Place the fluid bag in the water upside down (with the connection between the bag and line out of the water) for five to ten minutes until the fluids are approximately body temperature (or a bit cooler).
Safety note: Do NOT microwave the fluids. They can become too hot for your dog and can burn him or her (and you).
The veterinary team is here to help
I hope that you now feel more confident in your ability to give your dog subcutaneous fluids. While it may feel outside your comfort zone at first, I believe that you can do it!
However, if you have tried administering subcutaneous fluids at home and it wasn’t for you, I want you to know that’s ok too! Whether you (or your dog) aren’t a fan of needles, it was difficult to restrain your dog, or something else happened, giving fluids can be challenging.
If you encounter some bumps in the road, please discuss your experience with your veterinary team. They would be happy to give you more tips in person if you want to keep trying. Or, if you have decided it is best for you and your dog not to keep doing SQ fluids at home, they can help you develop a new plan.
Have you given your dog subcutaneous fluids?
Please comment below to share your experience and any tips you want to give to other readers.
My old dog was on 48 hours at the vet he had kidney disease and his blood had improved a bit when I got him home the first he did was drink water but just stop he want to his water bowl, countless times to drink I try so hard to get him to have some he just would not I stay up all night try lot of things the last thing I try was putting a little bit of water in his bowl he he did drink it but had been without water for to long
Why did he drink water when he got home then could not until I put the smallest bit water in his bowl
If I did this at first or work out this within a few hours would there be a chance he would still be here
Dear Maria,
I am so sorry for the loss of your senior boy. The intensive fluid therapy he received at the vet clinic was able to improve his kidney function a bit and also helped him to feel better. This is probably why he was willing to drink some water when he first arrived back home. But his kidneys continued to decline and after his blood levels increased again, he probably started to feel bad and did not want to drink anymore. Unfortunately, this is how kidney failure tends to progress and there is nothing else you could have done to stop it. You did not do anything wrong. I hope with time your heart will heal and you will be comforted knowing your pup lived a good life. May his memory stay with you always and be a blessing to you. ♥
My dog had to have a tox screen and subcutaneous fluids and active charcoal approximately 56 hours ago due to eating something he shouldn’t have (edible delta 8 gummie)
He’s basically fine now but he’s sore on his side around his ribs still… is this Normal? Possible from the needle site or the fluid settling there?
Hi Monica,
I am glad your pup is doing ok and was able to recover from his naughty adventure! While I guess it is possible he could be extra sensitive to where the needle was placed, I am not used to seeing subcutaneous fluids cause pain in my patients. The needle stick should be similar to when receiving a vaccine and should not be an issue after the fluids have been administered. I think it would be wise to call your vet and let them know about this. They can advise you if a follow up exam is needed or if you should be concerned. Take care!
Hi I’ve been giving my dogs fluids and today when I have it to her I noticed blood coming out of her mouth. Not a crazy amount but enough to be concerning. What should I do
Hi Shelly,
Please contact your vet right away! This sounds like it could be an emergency. Hoping your pup will be ok and you can get some answers quickly.
When my vet tech showed me how to administer the fluids, they recommended squeezing the bag instead of it hanging so that the fluids move faster (22 gauge). We’ve been trying this for over a week and our pup whines and cries the whole time (which only lasts a few minutes). How would you suggest reducing pain? Is it the squeezing of the bag? Should I be warming the fluids? Any guidance would be greatly appreciated, because at this point her stress seems counterproductive.
Hi Maria,
These are all great questions and I’m so glad you are reaching out for support. Without being present when the fluids are given to really assess the situation it is hard to make specific recommendations, but I do have a couple of ideas. Squeezing the bag is very common and normally does not cause discomfort. But when you squeeze the bag, you are forcing the fluid out at a higher rate so it could be causing extra pressure and a negative sensation under the skin. Some pups are just a little overly sensitive. 🙂 You can try hanging the bag and letting gravity do the work to see if it changes how your girl responds. Also, you could use a larger gauge needle. I know it seems like a larger needle would be more painful but it’s just a tiny quick prick and then it’s over. The larger needle will allow better/faster flow and may actually increase your dog’s comfort level. I typically use an 18-gauge needle when I administer fluids to my own patients. You could even try one step up and see how it works with a 20g. I will sometimes warm fluids if I am afraid of making my patient cold or significantly dropping their body temperature. This is more common practice with very tiny dogs or animals under sedation. I am not sure the warming will prevent whining or discomfort and it is hard to get the ideal temperature without melting the fluid bag or risking a burn. You can also try some positive reinforcement while the fluids are being given. Maybe let your pup lick some peanut butter or a frozen treat (as long as the treat is compatible with your dog’s diet and medical concerns) so that fluids are associated with a fun happy experience. I hope this will help guide you a bit. Wishing you both the best and keep up the good work!
I am presently administering Sub-Q fluids to my 7 pound Min-Pin Lucy. I have always had an aversion to needles used in the medical practice, but it was explained to me that this is her only opportunity at a longer life due to her advanced stage 4 kidney failure. I do it twice a day.
I love her dearly, and she loves me too but this disease will take her from me soon. We have had 12 wonderful years together and I already miss her so much. All dogs go to heaven, I hope I do so I can see her again.
Dear George,
I am sorry Lucy’s health is declining but glad to hear the daily fluids are helping to prolong her life. It is clear she is dearly loved and I am certain she knows. Here is a link to another article that may be helpful when you have to think about making some tough decisions: Preparing for Your Dog’s Euthanasia: 10 Thoughts for Peace
Hoping you can make the most of the time you have left and fill each day with joy. Praying for your strength and comfort. Bless you both.
Hi, i have a 14 year old dog and i gave her the subcutaneous fluids last night and the fluids migrated to her left side all the way back to her back leg. Now, today, she is in pain when i barely touch her left side or left leg. Is this normal?
Hi Kirsten,
It is normal for the subcutaneous fluids to move under the influence of gravity. But this should not cause pain and the fluids should be absorbed rather quickly. Please contact your vet about this new pain you are noticing in your senior dog. Hoping all is well and wishing you both the best.
Hi there,
I’ve been giving my dog sub q fluids for a few weeks after a new diagnosis of stage II CKD. While most of the process is easy at this point, I am continuing to struggle with figuring out the true level of fluid in the bag. It doesn’t seem as simple as just looking at the level on the bag; when I hold it taut, it’s a completely different level – sometimes up to a 150 ml difference. Am I doing something wrong? I’ve heard that there’s possibly not enough air in the bag,,,but I’ve also heard I’m not supposed to re-spike the bag due to the possibility of introducing bacteria into the fluid bag. Any guidance is appreciated!
Hi M,
Yes, those fluid bags can be a bit tricky at times! I usually just leave them hanging and try not to squeeze the bag when determining how much fluid is still inside. I completely understand what you are talking about and sometimes I have difficulty making this determination when it seems like the plastic is suctioning in on itself at the top of the bag. It might be worthwhile to take the fluid bag with you to your vet’s office and have them take a look at it. They can let you know what level you are currently at and see if there is anything they can do to make reading the measurements easier.
Approximately 21 years ago I had a border collie that had surgery at Va Tech and was diagnosed with liver cancer and given 10 months to live. A year came and went, then 2 years and into the 3rd year she became very sick again with vomiting and syncope upon standing. I took her back to Tech and they were very surprised to see that she was still alive and admitted that they must have made a mistake with the diagnosis. They did tests and suggested more surgery but I wanted to take her home and think about it for a few days. They agreed to my decision and asked that I bolus in sub-q fluids during that time. I am a retired nurse, so I had no problem with this decision due to my experience with IV’s. They showed me how to do the procedure and I did this for 3-4 days (no problems with the procedure) before deciding to have her put down due to that fact that she continued to worsen and also that she was 14 years old. At this age I couldn’t see putting her back through surgery again.
So if you need to give sub-q fluids to your dog, do so. It is not a difficult process and your vet is there to show you how and assist you if needed.
Hi Lynn,
Thank you for sharing your story and experience with our readers. This is great advice, and I am certain it will be helpful for someone in a similar situation. Best wishes!
my 9 year old dog had subcutaneous fluids given to her by her vet on Monday 8/21/2023. I read that it’s not uncommon for a dog to not feel the need to drink water for a bit after receiving the fluids. she’s 20lbs and received 200 of the fluid and is not drinking water. she’s been given low sodium chicken broth in her water and I gave her a syringe of pedialyte. when should I really worry about her water consumption? please help 🥺
Hi Shawna,
I understand why you are concerned about your dog’s health and well-being. While subcutaneous fluids can help with dehydration, I am not sure you could give enough to keep a dog feeling hydrated for more than several hours. It worries me that your pup has gone so many days without drinking water and eating. I highly recommend you contact your vet and update them on this ongoing situation. Hoping you can get the answers you need soon and praying for a positive outcome for your sweet girl.